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Dihydrotachysterol A synthetic analogue of vit D2 thatis much less active in antirachitic tests, but directly mobilizescalcium from bone after 25-hydroxylation in liver, and doesnot require PTH dependent activation in the kidney.
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There is circumstan-tial neuropathologic and amyloid imaging evidence thatamyloid may be deposited up to 15 years prior to diag-nosis (Rowe et al.
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